| Primary Identifier | MGI:6260024 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Thoc7 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GGCCTTAATAAAGTTCCACC and GGTATATCTGCCTGTCCTAG, which resulted in a 569 bp deletion beginning at Chromosome 14 position 13,954,335 bp and ending after 13,954,903 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000517611 (exon 2) and 451 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 6 and early truncation 8 amino acids later. |
