|  Help  |  About  |  Contact Us

Allele : Pcdhg<em12Rwb> protocadherin gamma cluster; endonuclease-mediated mutation 12, Robert W Burgess

Primary Identifier  MGI:6285787 Allele Type  Endonuclease-mediated
Attribute String  Modified isoform(s) Gene  Pcdhg
Inheritance Mode  Not Specified Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  This allele was generated through shotgun CRISPR/Cas9 editing using pooled sgRNAs that targeted each variable exon of the Pcdhg cluster and this allele was found to have a fusion between exons A5 and B8, and additional junctions between A1 and A4, A12 and A9, and B6 and A6 with an insertion of a transposable element and sequence from Anp32a exons 4-7 3-prime of exon A5, which, in sum, left only the variable exons C3, C4, and C5 intact.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • 3R1,
  • 3R1
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories