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Allele : Pfn3<em3Hsc> profilin 3; endonuclease-mediated mutation 3, Hubert Schorle

Primary Identifier  MGI:6384217 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Pfn3
Strain of Origin  (C57BL/6 x CBA)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 genome editing was used to delete 29 bp causing a frameshift in the reading frame that leads to a premature stop codon after amino acid 15. qRT-PCR, Western blotting, and immunohistochemistry confirmed the deletion in the testes of homozygous mutant mice.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Pfn3delta29,
  • Pfn3delta29
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories