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Allele : Pcdhg<em41Rwb> protocadherin gamma cluster; endonuclease-mediated mutation 41, Robert W Burgess

Primary Identifier	MGI:6284353	Allele Type	Endonuclease-mediated
Attribute String	Modified isoform(s)	Gene	Pcdhg
Inheritance Mode	Not Specified	Strain of Origin	C57BL/6J
Is Recombinase	false	Is Wild Type	false

molecularNote

This CRISPR/Cas9 mediated allele has a 13bp deletion (TACGTTTATGGGC) in variable exon C4 from coding base pair 85-97, causing a frameshift beginning at amino acid 29 of C4, but no other exons are mutated.

mutations:
Intragenic deletion

synonyms:
C4KO,
C4KO

earliestPublication:
Garrett AM, et al. (2019) CRISPR/Cas9 interrogation of the mouse Pcdhg gene cluster reveals a crucial isoform-specific role for Pcdhgc4. PLoS Genet 15(12):e1008554

1 Feature

Genome

0 Expresses

1 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

3 Publication categories

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