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Allele : Itgam<m2Btlr> integrin alpha M; mutation 2, Bruce Beutler

Primary Identifier  MGI:6285545 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Itgam
Inheritance Mode  Recessive Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
description  https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3757
molecularNote  ENU-induced C to T transition at base pair 128,081,634 (v38) on chromosome 7, or base pair 18,995 in the GenBank genomic region NC_000073. The mutation corresponds to residue 837 in the mRNA sequence NM_001082960 within exon 8 of 30 total exons. The mutation results in an alanine to valine substitution at position 245 (A245V) in the CD11b protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • obscured,
  • obscured
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories