Primary Identifier | MGI:6285545 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Itgam |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3757 |
molecularNote | ENU-induced C to T transition at base pair 128,081,634 (v38) on chromosome 7, or base pair 18,995 in the GenBank genomic region NC_000073. The mutation corresponds to residue 837 in the mRNA sequence NM_001082960 within exon 8 of 30 total exons. The mutation results in an alanine to valine substitution at position 245 (A245V) in the CD11b protein. |