| Primary Identifier | MGI:6317361 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Dennd5b |
| Strain of Origin | (C57BL/6 x CBA)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Using custom zinc finger nucleases, exons in the 5' one-third of the gene were targeted. ZFN RNA was microinjected into pronuclei of fertilized B6CBAF1 mouse embryos. This led to the establishment of a line with a biallelic 19 bp deletion (GGGTCTTCAGTCAAAAGAA) in exon 4 in the DENN domain of the encoded peptide. |
