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Allele : Ripk1<em1Xlin> receptor (TNFRSF)-interacting serine-threonine kinase 1; endonuclease-mediated mutation 1, Xin Lin

Primary Identifier  MGI:6363437 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Ripk1
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  Using CRISPR/Cas9 technology with an sgRNA targeting the sequence around lysine codon 376 plus a donor oligonucleotide containing sequence for a an arginine codon at that position, an allele was created with an-A to-G substitution leading to a p.K376R substitution in the Intermediate Domain.
  • mutations:
  • Single point mutation
  • synonyms:
  • Ripk1<K376R>,
  • Ripk1<K376R>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories