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Allele : Secisbp2<tm1.2Amdu> SECIS binding protein 2; targeted mutation 1.2, Alexandra M Dumitrescu

Primary Identifier	MGI:6323602	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Secisbp2
Transmission	Germline	Strain of Origin	C57BL/6J
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxp site was inserted upstream of exon 14 and an FRT-flanked neomycin resistance cassette and a second loxP site were inserted downstream of exon 14. Flp-mediated recombination removed the neo cassette and cre-mediated recombination deleted exon 14.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

earliestPublication:
Fu J, et al. (2017) Thyroid Hormone Metabolism Defects in a Mouse Model of SBP2 Deficiency. Endocrinology 158(12):4317-4330

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

4 Publication categories

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