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Allele : Orc1<tm1.1Gle> origin recognition complex, subunit 1; targeted mutation 1.1, Gustavo Leone

Primary Identifier	MGI:6355393	Allele Type	Targeted
Attribute String	Conditional ready	Gene	Orc1
Transmission	Germline	Strain of Origin	Not Specified
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxP site was inserted upstream of exon 9. An FRT-flanked neomycin selection cassette with a 3' loxP site was inserted downstream of exon 14. Flp-mediated recombination removed the neomycin selection cassette and left exons 9-14 floxed.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Orc1<f>,
Orc1<f>

earliestPublication:
Okano-Uchida T, et al. (2018) Endoreduplication of the mouse genome in the absence of ORC1. Genes Dev 32(13-14):978-990

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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