Primary Identifier | MGI:6382179 | Allele Type | Targeted |
Attribute String | Inducible, Recombinase | Gene | Aldh1b1 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Induced With | tamoxifen | Is Recombinase | true |
Is Wild Type | false |
molecularNote | The targeting construct consisting of the bicistronic Aldh1b1/P2A/CreERT2 transgene followed by the FRT-PGKneo- pA-FRT selection cassette was inserted in the endogenous Aldh1b1 locus to replace the coding region of mouse Aldh1b1 gene. The neo selection cassette was removed by Flp recombinase. |