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Allele : Inava<tm1.1Itl> innate immunity activator; targeted mutation 1,1, inGenious Targeting Laboratory
Primary Identifier  MGI:6356370 Allele Type  Targeted
Attribute String  Null/knockout Gene  Inava
Transmission  Germline Strain of Origin  (C57BL/6NTac x 129S6/SvEvTac)F1
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 2-8 were replaced with a loxP-flanked neomycin selection cassette. The neo cassette was removed via Cre-mediated recombination. Immunoblot analysis confirmed the absence of protein expression in intestinal epithelial monolayers derived from organoids and intestinal epithelial cells isolated from the colon of homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • C1orf106<->,
  • C1orf106<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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