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Allele : Cd80<em2Okat> CD80 antigen; endonuclease-mediated mutation 2, Taku Okazaki
Primary Identifier  MGI:6356537 Allele Type  Endonuclease-mediated
Gene  Cd80 Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR mediated recombination introduced three nucleotide substitutions of a CTG to GAG resulting in a L107E missense mutation. This mutation prevents the formation of the cis-CD274/CD80 duplex.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Cd80<L107E>,
  • Cd80<L107E>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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