| Primary Identifier | MGI:6356681 | Allele Type | Targeted |
| Attribute String | Modified isoform(s) | Gene | Ripk1 |
| Transmission | Germline | Strain of Origin | C57BL/6NTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Sequence 5'-ATTCAGATTGGA-3', encoding RIP homotypic interaction motif (RHIM) residues IQIG, was replaced with 5'-GCTGCGGCTGCA-3', coding for AAAA. An FRT site flanked neomycin selection cassette inserted into intron 9 at position chr13:34,029,090 (GRCm38/mm10 assembly) was deleted from the targeted embryonic stem cells before microinjection. |
