Primary Identifier | MGI:6357923 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Set |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | An FRT flanked neo cassette and loxP site were inserted upstream of exon 2 and a loxP site was inserted downstream of exon 2 via homologous recombination. Cre mediated recombination removed exon 2. Western blot analysis confirmed the absence of protein expression in homozygous embryos. |