Primary Identifier | MGI:6357985 | Allele Type | Targeted |
Attribute String | Modified isoform(s) | Gene | Kat5 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Specific knockout of the Tip55 isoform of Kat5 by targeting a construct to the Kat5 locus that fuses the last four exons and removes the intervening introns, one of which is retained in the Tip55 transcript. The resulting mouse expresses all other Kat5 isoforms normally but not Tip55. |