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Allele : Dicer1<em3Glo> dicer 1, ribonuclease type III; endonuclease-mediated mutation 3, Guillermina Lozano

Primary Identifier	MGI:6364607	Allele Type	Endonuclease-mediated
Attribute String	Null/knockout	Gene	Dicer1
Strain of Origin	Not Specified	Is Recombinase	false
Is Wild Type	false

molecularNote

This allele was generated using CRISPR/Cas9 technology with an sgRNA and a template oligonucleotide. Two nucleotides were deleted from serine codon 1712, causing a reading frame shift and a premature stop codon.

mutations:
Intragenic deletion

synonyms:
Dicer1<->,
Dicer1<->

earliestPublication:
Aryal NK, et al. (2019) Constitutive Dicer1 phosphorylation accelerates metabolism and aging in vivo. Proc Natl Acad Sci U S A 116(3):960-969

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

2 Publication categories

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