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Allele : Amigo2<em1(IMPC)J> adhesion molecule with Ig like domain 2; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6380687 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Amigo2
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CTTTGTGGCATCCACTTAGC and TTGACAGCTCTAGGCAGGGT, which resulted in a 1531 bp deletion beginning at Chromosome 15 position 97,244,981 bp and ending after 97,246,511 bp (GRCm38/mm10). This mutation deletes 1531 bp of ENSMUSE00000505071 (exon 2) and is predicted to cause a change of amino acid sequence after residue 9 and early truncation 23 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories