| Primary Identifier | MGI:6369043 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Timeless |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Using CRISPR/Cas9 technology with sgRNAs and a 200-nt single-stranded oligodeoxynucleotides (ssODN), a mutation was introduced to change arginine codon 1078 to a stop codon (p.R1078*). This mutation mimics the p.R1081* found in familial advanced sleep phase (FASP) patients. |
