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Allele : Serpinb2<em1Asuh> serine (or cysteine) peptidase inhibitor, clade B, member 2; endonuclease-mediated mutation 1, Andreas Suhrbier

Primary Identifier  MGI:6402920 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Serpinb2
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  The active site (P1) Arg38020 (codon AGA) of Serpinb2 was changed to Ala380 (codon GCA); i.e. nucleotides 1222 and 1223 (with reference to accession NM_011111.4) were changed from AG to GC. Two silent mutations were also introduced to prevent cutting of the oligonucleotide during genome editing.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • SerpinB2<R380A>,
  • SerpinB2<R380A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

2 Publication categories