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Allele : Phlpp1<tm1.2Shbi> PH domain and leucine rich repeat protein phosphatase 1; targeted mutation 1.2, Shigeki Shimba

Primary Identifier  MGI:6415193 Allele Type  Targeted
Attribute String  Null/knockout Gene  Phlpp1
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  A DNA fragment carrying a 34bp loxP sequence and Pgk-1 promoter-driven neomycin phosphotransferase gene (Pgk-neo) flanked by two Flp recognition target (frt) sites was inserted into the site 233bp upstream of exon 4. Another loxP site was introduced into the site 223bp downstream of exon 4. Exon 4 and the neomycin selection cassette were removed via Cre-mediated recombination in the germline.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Scop KO,
  • Scop KO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories