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Allele : Scimp<em1Adiuj> SLP adaptor and CSK interacting membrane protein; endonuclease-mediated mutation 1, MODEL-AD Center

Primary Identifier  MGI:6444735 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Scimp
Strain of Origin  B6.Cg-Apoe<tm1.1(APOE*4)Adiuj> App<em1Adiuj> Trem2<em1Adiuj>/J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 genome editing using a single guide RNA (ACAGGCAAGAGGACAAGTCC) is designed to introduce a T-to-C point mutation upstream of the gene locus.
  • mutations:
  • Single point mutation
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

2 Publication categories