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Allele : Spaca6<em2Osb> sperm acrosome associated 6; endonuclease-mediated mutation 2, Research Institute for Microbial Diseases, Osaka University

Primary Identifier	MGI:6437562	Allele Type	Endonuclease-mediated
Attribute String	Null/knockout	Gene	Spaca6
Strain of Origin	(C57BL/6NJcl x DBA/2NJcl)F2	Is Recombinase	false
Is Wild Type	false

molecularNote

CRISPR/Cas9 technology targeting the first coding exon and the intron downstream of the last coding exon generated an 8,085 bp deletion and a 4 bp insertion.

mutations:
Intragenic deletion,
Insertion

synonyms:
Spaca6 del,
Spaca6 del

earliestPublication:
Noda T, et al. (2020) Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm-oocyte fusion in mice. Proc Natl Acad Sci U S A 117(21):11493-11502

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

4 Publication categories

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