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Allele : Gcg<em1Dvs> glucagon; endonuclease-mediated mutation 1, David V Serreze

Primary Identifier  MGI:6455401 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Gcg
Strain of Origin  NOD.Cg-Prkdc<scid> Il2rg<tm1Wjl>/SzJ Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 genome editing is used to create an in-frame deletion in exon 3 - specifically within the 87 nucleotides encoding the 1-29 residues. Founder male 18-1 was identified with a 91 bp deletion including 28 of the first 29 amino acids of the gene.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Gcg1-29KO,
  • Gcg1-29KO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

2 Publication categories