| Primary Identifier | MGI:6466743 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Nlrc3 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | LoxP sites and an frt-flanked neomycin selection cassette was inserted to flank exons 2 and 3. Cre-mediated recombination in the germline resulted in the deletion of a 2.5 kb genomic region, which is expected to result in deletion of 661 amino acids encoding the N-terminal caspase recruitment domain (also known as CARD) and the central nucleotide-binding domain (also known as NACHT) of the encoded protein. |
