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Allele : Izumo1<em1Nino> izumo sperm-egg fusion 1; endonuclease-mediated mutation 1, Naokazu Inoue
Primary Identifier  MGI:6511748 Allele Type  Endonuclease-mediated
Attribute String  Modified isoform(s) Gene  Izumo1
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 genome editing technology was used to generate a nine-base deletion adjacent to the initial IZUMO1_v1 methionine start codon ( IZUMO1_v1 (p.Met1del) / IZUMO1_v2 (p.Ala30-Met32del). A reduced amount of encoded protein is expressed via an alternative splice codon (IZUMO1_v2).
  • mutations:
  • Intragenic deletion
  • synonyms:
  • IZUMO1_v1 KO,
  • IZUMO1_v1 KO,
  • Izumo1-KO,
  • Izumo1-KO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories





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