| Primary Identifier | MGI:6695108 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Tmem175 |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9 technology generated a TC to CG change resulting in an isoleucine to threonine substitution at residue 390 (p.I390T). This corresponds to a common human M393T variant associated with increased risk of developing Parkinson's disease. |