| Primary Identifier | MGI:6753234 | Allele Type | Targeted |
| Attribute String | Modified regulatory region | Gene | Rr27 |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The ICR (2.4 kb BglII fragment with chromatin insulation, promoter silencing and imprinting (differential methylation) function) between the Igf2 and H19 genes was replaced with a loxP site flanked neomycin resistance gene cassette and a 2.4 kb sequence containing two copies of the chicken beta globin chromatin insulator ((ChbetaGI)2). The neo cassette was removed through subsequent cre-mediated recombination. |
