| Primary Identifier | MGI:6728127 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Otop1 |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas genome editing technology was used to generate a 166 nucleotide deletion of genomic sequences in exon 1, resulting in early termination in exon 2. Two founders were generated with no differences in experimental observations. The loss of OTOP1 protein in the homozygous mutants was verified by immunostaining using OTOP1 antibodies. |
