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Allele : Cdh5<em1(cre/ERT2)Smoc> cadherin 5; endonuclease-mediated mutation 1, Shanghai Model Organisms Center

Primary Identifier	MGI:6724355	Allele Type	Endonuclease-mediated
Attribute String	Inducible, Recombinase	Gene	Cdh5
Strain of Origin	C57BL/6JSmoc	Induced With	tamoxifen
Is Recombinase	true	Is Wild Type	false

molecularNote

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Cdh5 gene stop codon site via CRISPR/Cas9 mediated recombination.

mutations:
Insertion

synonyms:
Cdh5-2A-CreERT2,
Cdh5<em1(2A-CreERT2-WPRE-polyA)Smoc>,
Cdh5<em1(2A-CreERT2-WPRE-polyA)Smoc>,
Cdh5-2A-CreERT2

earliestPublication:
Liu K, et al. (2022) Lineage tracing clarifies the cellular origin of tissue-resident macrophages in the developing heart. J Cell Biol 221(6)

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

5 Carried By

1 Driven By

4 Publication categories

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