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Allele : Setd1a<em1Yzhg> SET domain containing 1A; endonuclease-mediated mutation 1, Yi Zhang
Primary Identifier  MGI:7378548 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Setd1a
Strain of Origin  (C57BL/6 x DBA/2)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology targeted exon 15 and generated an 8 bp deletion that causes a frameshift and premature translation termination, mimicking the human loss-of-function mutations in patients with schizophrenia.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories





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