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Allele : Rnaseh2a<tm1.1Crh> ribonuclease H2, large subunit; targeted mutation 1.1, Robert J Crouch

Primary Identifier  MGI:7311688 Allele Type  Targeted
Attribute String  Not Specified Gene  Rnaseh2a
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  A serine substitution for glycine 37 (G37S) near the catalytic center on the RNase H2A subunit, a mutation associated with the human Aicardi-Goutieres syndrome, was introduced into this highly conserved residue of the catalytic subunit. Cre-mediated recombination removed the floxed selection cassette.
  • mutations:
  • Single point mutation
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories