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Allele : Cfap65<em1Yqt> cilia and flagella associated protein 65; endonuclease-mediated mutation 1, Yue-Qiu Tan

Primary Identifier	MGI:7316618	Allele Type	Endonuclease-mediated
Attribute String	Null/knockout	Gene	Cfap65
Inheritance Mode	Not Specified	Strain of Origin	C57BL/6
Is Recombinase	false	Is Wild Type	false

molecularNote

CRISPR/Cas9 technology deleted exons 4 through 11. Western blot analysis confirmed the absence of protein expression in the testes of homozygous mutant males.

mutations:
Intragenic deletion

synonyms:
Cfap65<->,
Cfap65<->

earliestPublication:
Wang W, et al. (2021) CFAP65 is required in the acrosome biogenesis and mitochondrial sheath assembly during spermiogenesis. Hum Mol Genet 30(23):2240-2254

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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