| Primary Identifier | MGI:7327509 | Allele Type | Targeted |
| Attribute String | Conditional ready | Gene | Il23r |
| Transmission | Germline | Strain of Origin | C57BL/6N-A<tm1Brd> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The L1L2_Bact_P cassette was inserted at position 67455672 of Chromosome 6 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon(s) at position 67456563. The critical exon(s) is/are thus flanked by loxP sites. A âconditional readyâ (floxed) allele was created by flp recombinase expression which removed the lacZ and neomycin selection cassette. |
