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Allele : Per2<em1Cmsu> period circadian clock 2; endonuclease-mediated mutation 1, Cam-Su Genomic Resource Center
Primary Identifier  MGI:7325473 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Per2
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated a valine to glycine (V721G; GTT to GGC) and leucine to glycine (L722G; CTG to GGC) substitutions at amino acids 721 and 722, respectively, in the PCD domain. These mutations correspond to the human V729G/L730G mutation that abolishes the PER2-CK1 association.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Per2<m>,
  • Per2<m>,
  • PER2<V721G/L722G>,
  • PER2<V721G/L722G>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories





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