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Allele : Kirrel3<em1Jfcl> kirre like nephrin family adhesion molecule 3; endonuclease-mediated mutation 1, Jean-Francois Cloutier

Primary Identifier  MGI:7327432 Allele Type  Endonuclease-mediated
Gene  Kirrel3 Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated a CAG to GCC codon change in exon 4 resulting in a glutamine to alanine substitution at amino acid 128 (p.Q128A). This mutation abolishes Kirrel3 dimerization.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Kirrel3<Q128A>,
  • Kirrel3<Q128A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories