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Allele : Trpv6<tm1.1Pgg> transient receptor potential cation channel, subfamily V, member 6; targeted mutation 1.1, Peter G Gillespie
Primary Identifier  MGI:7484726 Allele Type  Targeted
Gene  Trpv6 Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  A methionine to cysteine substitution at amino acid 527 (p.M527C) was introduced in exon 13 and a loxP-flanked neomycin resistance cassette was inserted downstream of exon 14. The neomycin resistance cassette was removed via cre-mediated recombination. This mutation has been shown to increase sensitivity to methanethiosulfonate reagents.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • M527-Trpv6,
  • M527-Trpv6
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

3 Publication categories





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