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Allele : Nppb<em1Vmc> natriuretic peptide type B; endonuclease-mediated mutation 1, Vincent M Christoffels
Primary Identifier  MGI:7366919 Allele Type  Endonuclease-mediated
Attribute String  Modified regulatory region, Null/knockout Gene  Nppb
Strain of Origin  FVB/NRj Is Recombinase  false
Is Wild Type  false
molecularNote  The potential Nppa/Nppb regulatory region upstream of Nppb was targeted with sgRNAs (targeting GGTTAATTGATTAAAAGTGG and GGGAATGCCTCAGCTACTGT) using CRISPR/Cas9 technology, resulting in the deletion of enhancer Rr93033 and the Nppb gene.
  • mutations:
  • Intergenic deletion,
  • Intragenic deletion
  • synonyms:
  • RE2<->,
  • RE2<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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