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Allele : Ppp1r12a<tm1.1Nju> protein phosphatase 1, regulatory subunit 12A; targeted mutation 1.1, Model Animal Research Center of Nanjing University
Primary Identifier  MGI:7464858 Allele Type  Targeted
Attribute String  Not Specified Gene  Ppp1r12a
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Threonine codon 694 (ACA) in exon 15 was changed to alanine (GCA) (p.T694A) and a loxP site flanked neomycin resistance gene cassette was inserted into intron 14. The neo cassette was removed through subsequent Cre-mediated recombination. The mutation prevents phosphorylation of the residue.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • Mypt1<T694A>,
  • Mypt1<T694A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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