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Allele : Gt(ROSA)26Sor<em1(CAG-EGFP/Rpl10)Mgmj> gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, Martin G Myers, Jr
Primary Identifier  MGI:7467071 Allele Type  Endonuclease-mediated
Attribute String  Conditional ready, Reporter Gene  Gt(ROSA)26Sor
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Using CRISPR/Cas9 technology, a targeting vector CAG-FSF-LSL followed by an EGFP/Rpl10 fusion reporter gene under the control of the CAG promoter (CVM enhancer/chicken ACTB promoter) was inserted into the Gt(ROSA)26Sor locus. It is an Flp- and Cre-dependent reporter. The expression of the EGFP/Rpl10 fusion reporter gene requires the removal of both LSL by Cre and FSF by Flp recombinases.
  • mutations:
  • Insertion
  • synonyms:
  • Rosa26<RCFL-eGFP-L10a>,
  • Rosa26<RCFL-eGFP-L10a>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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4 Publication categories





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