Primary Identifier | MGI:7451131 | Allele Type | Endonuclease-mediated |
Attribute String | Conditional ready, Inducible, Recombinase | Gene | Ccna2 |
Strain of Origin | Not Specified | Induced With | tamoxifen |
Is Recombinase | true | Is Wild Type | false |
molecularNote | Using CRISPR/Cas9 technology, the CrexER (Cre-rox-ER-rox) was generated by the insertion of two rox sequences flanking ERT2, a cDNA encoding CrexER recombinase was inserted into the translational stop codon of the Ccna2 gene, following endogenous Ccna2 by the self-cleaving peptide 2A sequence. |