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Allele : Gt(ROSA)26Sor<em1(CAG-Ncre/vvd*,-vvd*/Ccre)Larc> gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, Tomoji Mashimo

Primary Identifier  MGI:7523854 Allele Type  Endonuclease-mediated
Attribute String  Inducible, Recombinase Gene  Gt(ROSA)26Sor
Strain of Origin  C57BL/6J Induced With  blue light exposure
Is Recombinase  true Is Wild Type  false
molecularNote  A 7.0 kb PA-Cre expression plasmid under the control of the CAG promoter was introduced at the Gt(ROSA)26Sor locus using the CRISPR/Cas9 system. PA-Cre consists of a split Cre (59/60) with each fragment complemented with nMag or pMag (respectively) and a nuclear localization sequence (NLS) (CreN59-nMag-NLS and NLS-pMag-CreC60), separated by P2A self-cleaving peptide sequence (2A). The nMag and pMag are part of Magnets protein derived from the fragments of photoreceptor gene product Vivid (VVD) from a filamentous fungi Neurospora crassa.
  • mutations:
  • Insertion
  • synonyms:
  • PA-Cre KI,
  • PA-Cre KI
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

2 Publication categories