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Allele : Daxx<em3Glo> Fas death domain-associated protein; endonuclease-mediated mutation 3, Guillermina Lozano

Primary Identifier  MGI:7539427 Allele Type  Endonuclease-mediated
Gene  Daxx Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  Serine codon 226 (TCC) in exon 3 was changed to alanine (GCT) (p.S226A) using an sgRNA (targeting GCGGGCCTCCTGCAAATACG) and an ssODN template with CRISPR/Cas9 technology. The mutation, in the histone binding domain of the encoded peptide, affects histone H3.3 binding.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Daxx<S226A>,
  • Daxx<S226A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories