| Help | About | Contact Us

Allele : Fto<em1Yqt> FTO alpha-ketoglutarate dependent dioxygenase; endonuclease-mediated mutation 1, Yue-Qiu Tan

Primary Identifier	MGI:7718677	Allele Type	Endonuclease-mediated
Attribute String	Null/knockout	Gene	Fto
Strain of Origin	Not Specified	Is Recombinase	false
Is Wild Type	false

molecularNote

CRIPSR/cas9 mediated recombination using guide RNAs targeting exon 3 created a 4 bp deletion.

mutations:
Intragenic deletion

earliestPublication:
Wu Y, et al. (2023) Fat mass and obesity-associated factor (FTO)-mediated N6-methyladenosine regulates spermatogenesis in an age-dependent manner. J Biol Chem 299(6):104783

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

2 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=76827074

MouseMine