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Allele : Gipr<tm1.1Dajl> gastric inhibitory polypeptide receptor; targeted mutation 1.1, David Lloyd

Primary Identifier	MGI:7519130	Allele Type	Targeted
Attribute String	Conditional ready	Gene	Gipr
Transmission	Germline	Strain of Origin	C57BL/6NTac
Is Recombinase	false	Is Wild Type	false

molecularNote

Exons 4 and 5 are flanked by loxP sites, and a positive selection marker (Puromycin resistance) flanked by frt sites was inserted into intron 5, then subsequently removed via FLP-mediated recombination in the germline.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Gipr<fl>,
Gipr<fl>

earliestPublication:
Killion EA, et al. (2018) Anti-obesity effects of GIPR antagonists alone and in combination with GLP-1R agonists in preclinical models. Sci Transl Med 10(472)

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

6 Publication categories

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