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Allele : Myh11<em2(cre/ERT2)Jifz> myosin, heavy polypeptide 11, smooth muscle; endonuclease-mediated mutation 2, Jifeng Zhang

Primary Identifier	MGI:7512810	Allele Type	Endonuclease-mediated
Attribute String	Inducible, Recombinase	Gene	Myh11
Strain of Origin	C57BL/6J	Induced With	tamoxifen
Is Recombinase	true	Is Wild Type	false

molecularNote

Using CRISPR/Cas9 technology, a cre/ERT2-P2A sequence was inserted into the endogenous Myh11 gene immediately after the first codon ATG in exon 2.

mutations:
Insertion

synonyms:
Myh11-CreER<T2-P2A>,
Myh11-CreER<T2-P2A>

earliestPublication:
Zhao Y, et al. (2023) Generating endogenous Myh11-driven Cre mice for sex-independent gene deletion in smooth muscle cells. JCI Insight 8(14):e171661

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

1 Driven By

2 Publication categories

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