| Primary Identifier | MGI:7567367 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Gipr |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Glutamic acid codon 350 (GAG) in exon 12 was changed to glutamine (CAG) (p.E350Q) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutation is the equivalent of the human p.E354Q mutation (SNP rs1800437) associated with a lower body mass index (BMI) and increased risk for type 2 diabetes (T2D). |
