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Allele : Spin4<em1Jbn> spindlin family, member 4; endonuclease-mediated mutation 1, Jeffrey Baron

Primary Identifier  MGI:7621834 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Spin4
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 genome editing technology was used to generate a truncating deletion of sequences starting before the start of the first Tudor domain of the encoded protein. This line has all 3 Tudor domains removed. Histone array analysis demonstrated that the histone-binding capacity of the truncated protein is abolished.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • long-deletion,
  • long-deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories