Primary Identifier | MGI:7584374 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Hspb6 |
Inheritance Mode | Not Specified | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 2 and exon 3 were selected as target sites. Western blot analysis demonstrated a significant reduction of HSPB6 and phosphorylated HSPB6 (P-HSPB6) protein levels in the aortic tissues of homozygous mutant mice. |