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Allele : Socs4<m1Nch> suppressor of cytokine signaling 4; mutation 1, Sandra E Nicholson

Primary Identifier	MGI:7587716	Allele Type	Chemically induced (ENU)
Attribute String	Null/knockout	Gene	Socs4
Strain of Origin	C3HeB/FeJ	Is Recombinase	false
Is Wild Type	false

molecularNote

ENU mutagenesis induced a C-to-T change in arginine codon 108 (CGA), changing it to a stop codon (TGA) (p.R108*).

mutations:
Single point mutation

synonyms:
Socs4<R108X>,
Socs4<R108X>

earliestPublication:
Kedzierski L, et al. (2014) Suppressor of cytokine signaling 4 (SOCS4) protects against severe cytokine storm and enhances viral clearance during influenza infection. PLoS Pathog 10(5):e1004134

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

3 Carried By

0 Driven By

5 Publication categories

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