Primary Identifier | MGI:7612306 | Allele Type | Targeted |
Attribute String | Recombinase | Gene | Neurog1 |
Transmission | Germline | Strain of Origin | (129S6/SvEvTac x C57BL/6NCrl)F1 |
Is Recombinase | true | Is Wild Type | false |
molecularNote | A targeting vector replaced the entire coding region of the Neurog1 gene with C-Cre (amino acids 60-343 in Ascl1 locus) modified with a nuclear-localization signal, GCN4 coiled-coil domain, and flexible linker. A neomycin cassette flanked by self-deletion anchor sites was present downstream of the C-Cre cassette. |